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Hyperbaric oxygen therapy (HBOT) clinic (Dive Medicine)

Hyperbaric oxygen therapy (HBOT) utilizes oxygen at higher than normal (14.7 PSI sea level) atmospheric pressure (hyperbaric) in order to increase the amount of oxygen in body tissues.

We are limited by the amount of oxygen we can get into our tissues by what our red blood cells can carry. At any given time, blood is being shunted to the tissues that have the highest immediate need for survival. When our tissues need to repair, we simply do not have the extra oxygen needed to do this effectively.

HBOT bypasses this factor. It is based upon gas laws. Under pressure, gas bubbles both becomes smaller and dissolve into fluid. This allows the oxygen to flood the plasma (portion of blood without the red blood cells) with oxygen. This, in turn, floods the tissues with oxygen. One of the great benefits of HBOT is that it slows cell death. When breathing oxygen under normal pressure, this does not happen.

This oxygen nourishes the tissue, nerves, mitochondria, and helps us to heal. The amount of oxygen in the brain during treatment increases to about 3X that of what the level normally is.

HBOT increases important cell transcription factors, including Humanin-peptide, which is made in the wall of the mitochondria of each cell and its function is to protect and repair the cell when it is under stress. This includes, cells of the neurological system, brain, organs, bones, and all cells of our body that contain mitochondria (that is every cell but red blood cells). HBOT also has been shown to increase adult stem cell activity, which is vital for repair. 

HBOT is great for all ages from young children up through the elderly. In children, HBOT research shows that it is a helpful therapy for ADD/ADHD, autism, brain-injuries, stroke, mitochondrial/genetic disorders, and both learning and growth delay.

In the elderly, HBOT slows aging by repairing tissue and increasing stem cell activity, helping with dementia, Alzheimer's, fatigue, insomnia, movement disorders, arthritis, pain, inflammation, neuropathy, mood, and memory loss.

We are nationally-certified in functional medicine dives by the International Board of Undersea Medicine (IBUM)

Oxygen is one of the most important nutrients for the completion of mitochondrial energy production. This is how our body produces energy in every cell of the body (aside from red blood cells, which only function is to carry oxygen to other tissues).

We need oxygen in order to heal damaged tissue and inflammation, regenerate damaged nerve tissue, regulate immune processes, nourish and heal the brain, as well as regulate brain function for energy, sleep, and mood. Oxygen has an integral role in helping us to fight infection. It has a role in the cardiovascular system, in regulating the delivery of oxygen to tissues and regulating blood pressure. 

There are two absolute contraindications to hyperbaric oxygen therapy: pneumothorax (collapsed lung) and inability to equalize pressure in the ears. We will work with you to make sure that you are able to equalize the pressure in your ears, or adjust the pressure accordingly. We also will not use this therapy in pregnancy.

HBOT does not hurt. It is very safe and well-tolerated. We ask that if you have any pain in your ears, you tell us, and we will adjust the pressure and help you to clear your ears. At times, it can feel like your ears need to “pop” for a couple hours to days after treatment, and this is normal and safe.

We use in patients with HBOT for ADD/ADHD, Chronic Fatigue, Lyme Disease and other infections, Retinitis Pigmentosa, ALS, Chronic Inflammatory Disease, TBI/concussion/brain fog, Macular Degeneration, Rheumatoid Arthritis, Alzheimer's Disease, Crohns and Ulcerative Colitis, Meniere's Disease, Anoxic Brain Injury, Migraines, Autism, Diabetes, Mitochondrial Disorders, Spinal Cord Injury, Fibromyalgia, Multiple Sclerosis, Bell's Palsy, Cancer, Infections, Raynaud's Syndrome, Trigeminal Neuralgia, Cerebral Palsy, Immune Dysfunction/autoimmunity, Mold toxicity, hormone balance, Anxiety/PTSD/Depression/Mental health, Reflex Sympathetic Dystrophy Vascular Disease, and many other things.

The mechanism by which this works is vast: it increases oxygen to the brain. The pressure we set is determined by what we are treating. The body will adapt by increasing or decreasing oxygen to the brain, depending upon what the goal is.

 

 

 

Many conditions that see improvement with HBOT rely on increased oxygen to tissue. In 75% of those with autism, there is hypoperfusion (decreased oxygen) to the brain. In TBI, migraines, brain fog, MS, Parkinsons, Dementia, the increased oxygen to the brain allows for balancing of neurotransmitters and healing of tissue.

HBOT has great efficacy in Lyme disease and cancer, as cancer cells and spirochetes (Lyme) thrive in low oxygen environments. When exposed to tissue-levels over 1000 times normal levels through HBOT, spirochetes and cancer cells begin to die.

In injury and arthritis, damaged capillary beds inhibit the supply of oxygen to the tissue. HBOT bypasses this and is able to bring oxygen to the damaged tissue, regardless. This is why HBOT is the designated treatment for non-healing ulcers and wounds.

Studies have shown that using HBOT at specified levels increased adult stem cell activity. HBOT increases our own antioxidant activity, collagen repair, angiogenesis (new blood flow), immune balance, and many other mechanisms by which it helps us to heal.

HBOT can enhance the effects of certain antibiotics, increasing white blood cell activity to fight infection and enhance immune response. It also enhances cell-signaling molecules, a huge factor in its effects.

We are currently offering bundle package pricing for Hyperbaric Oxygen Therapy.

Soft-chamber pricing is as follows:

20 hours = $1800.00*

40 hours = $3200.00*

60 hours = $4800.00*

80 hours = $6200.00*

Price per single one-hour session = $110.00

Steel-chamber pricing is as follows:

20 hours = $2400.00*

40 hours = $4320.00*

60 hours = $6240.00*

80 hours = $7950.00

Price per single one-hour session = $150.00

If you are not a current patient at Hope ND, you will need to undergo a pre-screen appointment prior to beginning treatment. Pre-screen appointment = $75.00.

Hyperbaric oxygen therapy is about repetition. Most conditions will require multiple sessions per week, in order to be most effective.

How quickly a patient responds is very individualized. In some cases, patients notice change right away, and for others, it can take over 20 or 40 hours to begin to notice change. 

It is important to note that even in the absence of immediate 'noticeable change,' there are mechanisms occurring on a cellular level that are beginning to heal tissue/nerves.

 

*Please note, these packages must be paid for up-front, in order to be eligible for bundle discounts. 

*We do not bill insurance for Hyperbaric Oxygen Therapy, as we do not utilize it for those conditions in which insurance coverage would apply. In those instances, you would be sent to a hospital for therapy. 

In a hospital, a single one-hour session can run up to $10,000.00 without insurance. If you are denied coverage in a hospital, please reach out to us to utilize the chambers at our office for these out-of-pocket costs

  1. Air or gas embolism

  2. Carbon monoxide poisoning

  3. Clostridial myositis and myonecrosis (gas gangrene)

  4. Crush injury

  5. Decompression sickness

  6. Non-healing wounds that meet selective criteria

  7. Severe blood loss leading to severe/life-threatening anemia

  8. Intracranial abscess

  9. Necrotizing soft-tissue infections

  10. Refractory osteomyelitis

  11. Complications of Radiation Therapy

  12. Compromised skin grafts and flaps (at risk of rejection/death)

  13. Thermal burns (generally deep-second degree and third degree burns)

  14. Idiopathic sudden sensorineural hearing loss 

Small sample of research studies into the use of Hyperbaric Oxygen Therapy for different conditions

Lyme Disease (Borrelia burgdorferi):

Hyperbaric oxygen therapy as an effective adjunctive treatment for chronic Lyme disease - ScienceDirect

Microsoft Word - Document1 (hbotxofpalmbeach.com)

Maintenance of infective Borrelia burgdorferi Sh-2-82 in 4% oxygen – 5% carbon dioxide in vitro (cdnsciencepub.com)

Borrelia burgdorferi membranes are the primary targets of reactive oxygen species - PubMed (nih.gov)

Vertigo/BPPV/Meniere's:

TREATMENT OF CHRONIC VERTIGO WITH HYPERBARIC OXYGEN - ScienceDirect

Sudden hearing loss and vertigo after tooth extraction successfully treated with combined therapy including HBO2: a case report. - Abstract - Europe PMC

Alternobaric and Hyperbaric Oxygen Therapy in the Immediate and Long-term Treatment of Meniere's Disease: Audiology: Vol 35, No 6 (tandfonline.com)

Infertility:

Hyperbaric oxygenation as a possible therapy of choice for infertility treatment - PubMed (nih.gov)

Hyperbaric Oxygen Treatment Ameliorates the Decline in Oocyte Quality and Improves the Fertility of Aged Female Mice - PubMed (nih.gov)

An evaluation of the effects on the ovaries of hyperbaric oxygen therapy in a rat model of premature ovarian failure created with cyclophosphamide - PubMed (nih.gov)

Clinical utility of hyperbaric oxygen therapy in genitourinary medicine - PubMed (nih.gov)

Wounds/burns/post-surgery/scarring:

Adjunctive hyperbaric oxygen therapy in severe burns: Experience in Taiwan Formosa Water Park dust explosion disaster - PubMed (nih.gov)

Hyperbaric oxygen and surgery - PubMed (nih.gov)

[Hyperbaric oxygen therapy in the treatment of wounds, in plastic and reconstructive surgery] - PubMed (nih.gov)

Hyperbaric oxygen in trauma and surgical emergencies - PubMed (nih.gov)

Hyperbaric Therapy For Wound Healing - StatPearls - NCBI Bookshelf (nih.gov)

Could hyperbaric oxygen be an effective therapy option for pathological scars? A systematic review and meta-analysis - PubMed (nih.gov)

Atherosclerosis, cholesterol, lipids, and insulin resistance:

Hyperbaric oxygen reduces the progression and accelerates the regression of atherosclerosis in rabbits - PubMed (nih.gov)

Hyperbaric oxygen therapy affects insulin sensitivity/resistance by increasing adiponectin, resistin, and plasminogen activator inhibitor-I in rats - PubMed (nih.gov)

Effect of Hyperbaric Oxygen Therapy (HBOT) on Insulin Resistance Associated with Abdominal Obesity in Wistar Rats with Dietary Sucrose-Induced Metabolic Syndrome - PubMed (nih.gov)

Hyperbaric oxygen treatment improves pancreatic β‑cell function and hepatic gluconeogenesis in STZ‑induced type‑2 diabetes mellitus model mice - PubMed (nih.gov)

Hyperbaric Oxygen Ameliorates Insulin Sensitivity by Increasing GLUT4 Expression in Skeletal Muscle and Stimulating UCP1 in Brown Adipose Tissue in T2DM Mice - PubMed (nih.gov)

Neurological conditions and enhanced brain function, post-concussion, TBI (traumatic brain injury):

Molecular and Therapeutic Aspects of Hyperbaric Oxygen Therapy in Neurological Conditions - PMC (nih.gov)

Effectiveness of hyperbaric oxygen therapy in the treatment of complex regional pain syndrome - PubMed (nih.gov)

Hyperbaric oxygen therapy can improve post concussion syndrome years after mild traumatic brain injury - randomized prospective trial - PubMed (nih.gov)

Hyperbaric oxygen therapy in children with post-concussion syndrome improves cognitive and behavioral function: a randomized controlled trial - PubMed (nih.gov)

Hyperbaric Oxygen Therapy Can Induce Angiogenesis and Regeneration of Nerve Fibers in Traumatic Brain Injury Patients - PubMed (nih.gov)

Hyperbaric oxygen therapy and promoting neurological recovery following nerve trauma - PubMed (nih.gov)

Hyperbaric Oxygen Alleviates Secondary Brain Injury After Trauma Through Inhibition of TLR4/NF-κB Signaling Pathway - PubMed (nih.gov)

Neuroprotective effect of hyperbaric oxygen therapy in brain injury is mediated by preservation of mitochondrial membrane properties - PubMed (nih.gov)

Hyperbaric oxygen may induce angiogenesis in patients suffering from prolonged post-concussion syndrome due to traumatic brain injury - PubMed (nih.gov)

A phase I study of low-pressure hyperbaric oxygen therapy for blast-induced post-concussion syndrome and post-traumatic stress disorder - PubMed (nih.gov)

Hyperbaric oxygen for severe traumatic brain injury: a randomized trial - PubMed (nih.gov)

Hyperbaric Oxygen Environment Can Enhance Brain Activity and Multitasking Performance - PubMed (nih.gov)

Cognitive enhancement of healthy older adults using hyperbaric oxygen: a randomized controlled trial - PubMed (nih.gov)

https://www.webmd.com/brain/news/20170720/oxygen-therapy-revives-toddlers-brain?ecd=soc_fb_171203_cons_news_oxygentherapyrevives&linkId=100000001502106&fbclid=IwAR3moqGu86_yu0aEpbI3DXwGLdux7EJyNVRh3czzgBYd54M-az94iULrhTo

Autism

Hyperbaric oxygen treatment in autism spectrum disorders | Medical Gas Research | Full Text (biomedcentral.com)

Randomized trial of hyperbaric oxygen therapy for children with autism - ScienceDirect

The effects of hyperbaric oxygen therapy on oxidative stress, inflammation, and symptoms in children with autism: an open-label pilot study - PubMed (nih.gov)

Hyperbaric oxygen therapy may improve symptoms in autistic children - PubMed (nih.gov)

Hyperbaric Oxygen Therapy Alleviates Social Behavior Dysfunction and Neuroinflammation in a Mouse Model for Autism Spectrum Disorders - PubMed (nih.gov)

Hyperbaric oxygen therapy in Thai autistic children - PubMed (nih.gov)

Hyperbaric oxygen therapy might improve certain pathophysiological findings in autism - PubMed (nih.gov)

The effectiveness of hyperbaric oxygen therapy (HBOT) in children with autism spectrum disorders - PubMed (nih.gov)

Diabetes, weight-loss, appetite-regulation, and metabolic syndrome

Hyperbaric oxygen treatment improves pancreatic β‑cell function and hepatic gluconeogenesis in STZ‑induced type‑2 diabetes mellitus model mice - PubMed (nih.gov)

Hyperbaric oxygen therapy affects insulin sensitivity/resistance by increasing adiponectin, resistin, and plasminogen activator inhibitor-I in rats - PubMed (nih.gov)

Effect of Hyperbaric Oxygen Therapy (HBOT) on Insulin Resistance Associated with Abdominal Obesity in Wistar Rats with Dietary Sucrose-Induced Metabolic Syndrome - PubMed (nih.gov)

Hyperbaric Oxygen Ameliorates Insulin Sensitivity by Increasing GLUT4 Expression in Skeletal Muscle and Stimulating UCP1 in Brown Adipose Tissue in T2DM Mice - PubMed (nih.gov)

Osteoporosis and bone injury

The effect of bone marrow concentrate and hyperbaric oxygen therapy on bone repair - PubMed (nih.gov)

Hyperbaric oxygen therapy improves angiogenesis and bone formation in critical sized diaphyseal defects - PubMed (nih.gov)

Effect of hyperbaric oxygen on demineralized bone matrix and biphasic calcium phosphate bone substitutes - PubMed (nih.gov)

Type 1 Diabetes 

Ghrelin system is involved in improvements in glucose metabolism mediated by hyperbaric oxygen treatment in a streptozotocin‑induced type 1 diabetes mouse model - PubMed (nih.gov)

PTSD

Hyperbaric oxygen for severe traumatic brain injury: a randomized trial - PubMed (nih.gov)

HBO and PTSD - The Wellness Lab

Hyperbaric oxygen therapy improves symptoms, brain's microstructure and functionality in veterans with treatment resistant post-traumatic stress disorder: A prospective, randomized, controlled trial - PubMed (nih.gov)

A phase I study of low-pressure hyperbaric oxygen therapy for blast-induced post-concussion syndrome and post-traumatic stress disorder - PubMed (nih.gov)

Long-COVID 19, Energy, Dysautonomia

Hyperbaric oxygen treatment for long coronavirus disease-19: a case report - PubMed (nih.gov)

Firefighters with Long COVID receive hyperbaric oxygen therapy - West Midlands Fire Service (wmfs.net)

Hyperbaric oxygen therapy improves neurocognitive functions and symptoms of post-COVID condition: randomized controlled trial - PubMed (nih.gov)

Case Study: Postural Orthostatic Tachycardia Syndrome - Carolina Functional Neurology Center (carolinafnc.com)

Effects of hyperbaric oxygen therapy on functional and structural connectivity in post-COVID-19 condition patients: A randomized, sham-controlled trial - PubMed (nih.gov)

Hyperbaric oxygen therapy for the treatment of long COVID: early evaluation of a highly promising intervention - PubMed (nih.gov)

Hyperbaric oxygen therapy for the treatment of long COVID: early evaluation of a highly promising intervention | RCP Journals

Pain, Inflammation, Injury, Fibromyalgia, headache/migraine:

Systematic review: The safety and efficacy of hyperbaric oxygen therapy for inflammatory bowel disease - PubMed (nih.gov)

Hyperbaric oxygen reduces inflammation, oxygenates injured muscle, and regenerates skeletal muscle via macrophage and satellite cell activation - PubMed (nih.gov)

Hyperbaric oxygen treatment decreases pain in two nerve injury models - PubMed (nih.gov)

Hyperbaric oxygen in chronic cluster headaches: influence on serotonergic pathways - PubMed (nih.gov)

Hyperbaric oxygen reduces inflammation, oxygenates injured muscle, and regenerates skeletal muscle via macrophage and satellite cell activation - PubMed (nih.gov)

Recovery of Repressed Memories in Fibromyalgia Patients Treated With Hyperbaric Oxygen - Case Series Presentation and Suggested Bio-Psycho-Social Mechanism - PubMed (nih.gov)

Hyperbaric oxygen therapy can diminish fibromyalgia syndrome--prospective clinical trial - PubMed (nih.gov)

Immune and cancer:

Hyperbaric Oxygen Therapy Represses the Warburg Effect and Epithelial-Mesenchymal Transition in Hypoxic NSCLC Cells via the HIF-1α/PFKP Axis - PubMed (nih.gov)

The impact of hyperbaric oxygen therapy on late radiation toxicity and quality of life in breast cancer patients - PubMed (nih.gov)

Efficacy of Metabolically Supported Chemotherapy Combined with Ketogenic Diet, Hyperthermia, and Hyperbaric Oxygen Therapy for Stage IV Triple-Negative Breast Cancer - PubMed (nih.gov)

Further application of hyperbaric oxygen in prostate cancer - PubMed (nih.gov)

Stroke

Hyperbaric Oxygen Therapy | Stroke (ahajournals.org)

Hyperbaric oxygen induces late neuroplasticity in post stroke patients--randomized, prospective trial - PubMed (nih.gov)

A Dual Role for Hyperbaric Oxygen in Stroke Neuroprotection: Preconditioning of the Brain and Stem Cells - PubMed (nih.gov)

Stem cell mobilization

Stem cell mobilization by hyperbaric oxygen - PubMed (nih.gov)

A Dual Role for Hyperbaric Oxygen in Stroke Neuroprotection: Preconditioning of the Brain and Stem Cells - PubMed (nih.gov)

Autism

Hyperbaric treatment for children with autism: a multicenter, randomized, double-blind, controlled trial - PubMed (nih.gov)

Hyperbaric oxygen treatment in autism spectrum disorders - PubMed (nih.gov)

https://www.bing.com/search?

q=xiong+hyperbaric+autism&cvid=15366dffe46d4388bf302f5797bba7e3&aqs=edge..69i57j69i64j69i60l3.3119j0j4&FORM=ANAB01&PC=DCTS

Dementia and Alzheimer's

Protective Effect of Hyperbaric Oxygen Therapy on Cognitive Function in Patients with Vascular Dementia - PMC (nih.gov)

Hyperbaric oxygen combined with donepezil in the treatment of vascular dementia | Chinese Journal of Physical Medicine and Rehabilitation;(12): 478-480, 2009. | WPRIM (bvsalud.org)

Hyperbaric oxygen therapy for Alzheimer's dementia with positron emission tomography imaging: a case report - PubMed (nih.gov)

Inhibition of Apoptosis by Hyperbaric Oxygen in a Rat Focal Cerebral Ischemic Model - Dali Yin, Changman Zhou, Ikuyo Kusaka, John W. Calvert, Andrew D. Parent, Anil Nanda, John H. Zhang, 2003 (sagepub.com)

 

Hyperbaric oxygen therapy improves neurogenesis and brain blood supply in piriform cortex in rats with vascular dementia: Brain Injury: Vol 24, No 11 (tandfonline.com)

https://www.bing.com/search?q=shapira+hyperbaric+alzheimers&cvid=b8a50dcff9dc45a0abe34bb721b92a2c&aqs=edge..69i57j69i64.12212j0j9&FORM=ANAB01&PC=DCTS

Hyperbaric oxygen therapy for vascular dementia - PubMed (nih.gov)

Arthritis

Hyperbaric oxygen protects mandibular condylar chondrocytes from interleukin-1β-induced apoptosis via the PI3K/AKT signaling pathway - PMC (nih.gov)

The Effects of Hyperbaric Oxygen on Rheumatoid Arthritis: A Pilot Study - PubMed (nih.gov)

Restless Leg Syndrome

New evidence for reduced leg oxygen levels in restless legs syndrome | Neurology

Cortisol levels and stress

Effect of hyperbaric conditions on plasma stress hormone levels and endothelin-1 - PubMed (nih.gov)

Hyperbaric stress in divers and non-divers: neuroendocrine and psychomotor responses - PubMed (nih.gov)

The influences of hyperbaric oxygen therapy with a lower pressure and oxygen concentration than previous methods on physiological mechanisms in dogs - PubMed (nih.gov)

Addiction

[Hyperbaric oxygenation in the treatment of patients with drug addiction, narcotic addiction and alcoholism in the post-intoxication and abstinence periods] - PubMed (nih.gov)

Interstitial Cystitis, bladder inflammation, urinary frequency, genital system

Effects of hyperbaric oxygen therapy on hydrochloric acid-induced interstitial cystitis in rats: a histological and ultrastructural study - PubMed (nih.gov)

Hyperbaric oxygen therapy for painful bladder syndrome/interstitial cystitis resistant to conventional treatments: long-term results of a case series in Japan - PubMed (nih.gov)

Safety and efficacy of hyperbaric oxygen therapy for the treatment of interstitial cystitis: a randomized, sham controlled, double-blind trial - PubMed (nih.gov)

Hyperbaric oxygen for the treatment of interstitial cystitis: long-term results of a prospective pilot study - PubMed (nih.gov)

Clinical utility of hyperbaric oxygen therapy in genitourinary medicine - PMC (nih.gov)

Hyperbaric Oxygen Therapy for Radiation Cystitis - PubMed (nih.gov)

Hydradenitis Suppurativa (HS) (inverse acne

A prospective randomized controlled trial assessing the efficacy of adjunctive hyperbaric oxygen therapy in the treatment of hidradenitis suppurativa - PubMed (nih.gov)

Hyperbaric Oxygen Therapy as an Adjunct to Surgical Treatment of Extensive Hidradenitis Suppurativa | SpringerLink

Allergic Rhinitis and Allergies

May Hyperbaric Oxygen Therapy Play a Role in the Treatment of Allergic Rhinitis? A Double- Blind Experimental Study in Rat Model Hyperbaric Oxygen Therapy on Allergic Rhinitis | SciTechnol

chamber room with oxygen cylinders_edited.jpg

Call 

603.554.1880

Email 

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Hope ND

Please note, we have a dog in clinic. If you have a severe allergy, please inform us before your visit

P (603) 554-1880

F (603) 213-6490

11 Powers St.

Milford, NH 03055

DrDBonfanti@gmail.com

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